When a drunk driver causes their parents’ deaths, the quintet of the title must learn to fend for themselves in this classic ’90s series, with stubbly college drop-out Charlie Salinger (Matthew Fox, who went on to star in Lost) taking charge of his younger siblings Julia (Neve Campbell), Bailey (Scott Wolf), Claudia (future Mean Girls star Lacey Chabert) and baby Owen.

All six seasons are available on Netflix now.