There's plenty of drama, intrigue and the return of some familiar faces on the wards of Holby City this autumn, as the latest preview reveals...

Holby City has released its autumn preview – and it’s packed with teasers galore.

It looks like the net could be closing in on maverick Professor John Gaskell (Paul McGann), as his friend and colleague Roxanna MacMillan (Hermione Gulliford) digs for information into his precious stem cell trial. And it seems it’s not long before Hanssen (Guy Henry) and Jac (Rosie Marcel) are onto him, too!

Holby Roxanna digs for dirt on Gaskell

Roxanna is onto Gaskell – but is she entering dangerous territory?

Meanwhile, after considering taking his own life a few weeks ago, it appears consultant Sacha Levy (Bob Barrett) hasn’t fully exorcised his inner demons. Will a close friend reach out to him when he needs them the most?

Elsewhere, it seems there could be love in the air for some of our Holby favourites. Will Jac and Fletch (Alex Walkinshaw) finally give into the feelings they’ve been battling against all this time? Will Xavier (Marcus Griffiths) and Donna (Jaye Jacobs) mix business with pleasure? Are lovebirds Dom (David Ames) and Lofty (Lee Mead) planning to start a family? And, could a new face on the wards pose a threat to ‘Berena’?

jac and fletch

Could love be in the air for Holby favourites Fletch (Alex Walkinshaw) and Jac (Rosie Marcel)?

Aside from new faces, some familiar ones will be returning, too. After leaving Holby earlier this year to start a new life with her ‘Mr T’, likeable surgeon Mo Effanga (Chizzy Akudolu) returns later this year.

Chizzy Akudolu plays Mo Effanga in Holby City

Surgeon Mo Effanga (Chizzy Akudolu) will be back on the wards this autumn

And, brace yourselves… after leaving the hospital under a cloud following a huge mental breakdown, neurosurgeon Guy Self (John Michie) is back! What brings him back? You’ll have to watch to find out…

Holby City is on Tuesdays at 8pm on BBC1