Hugely popular 1980s comedians The Comic Strip are reuniting in a one-off 60-minute film The Hunt for Tony Blair for Channel 4.

Billed as a ‘1950s-style fugitive film noir spoof’, the show will reunite Peter Richardson, Jennifer Saunders, Nigel Planer, Rik Mayall and Robbie Coltrane and add Stephen Mangan, James Buckley and Harry Enfield to the ensemble.

Channel 4’s creative boss Jay Hunt said: “Comic Strip defined comedy for a generation and it’s a real coup to have the team back tackling one of the most controversial subjects of our time in a way that only they can. Tony Blair on the run, Jennifer Saunders as Margaret Thatcher, a stellar cast and hotbed of political intrigue – I can’t wait to see the rushes.”

The show will follow Prime Minister Tony Blair (Stephen Mangan), wanted for murder and on the run. Escaping from Number 10 and leaving behind his adoring wife Cherie (Catherine Shepherd), Tony vows to clear his name no matter what the consequences.

But on a foggy London night, Tony has few friends willing to harbour a wanted man and with front pages demanding his capture, the PM has no choice but to disappear, with Inspector Hutton (Robbie Coltrane) and his sidekick (James Buckley) hot on his trail.

No word yet on a broadcast date.