The series, which will feature chat with celebrity guests, will mark former X Factor USA host and T4 presenter Steve’s return to weekends on Channel 4.
Channel 4 head of daytime David Sayer, said: “Steve and Lisa are the perfect pairing to present the show’s unique combination of celebrity chat, seasonal cooking and tips on how to entertain.
“It’s a great fit for 4’s schedule and will help our viewers make the most of their weekends.”
The hour-long shows are set to feature chefs including Heston Blumenthal, Raymond Blanc, Michel Roux Jnr, John Torode and Angela Hartnett.
They will cook seasonal recipes live on set in a family-style kitchen.
Weekend Kitchen With Waitrose starts on Channel 4 on Saturday, April 26.